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These are all meant to be taken on an as-needed basis, at the first sign of headache, and they include Sumatriptan (Imitrex); Zolmitriptan (Zomig); Rizatriptan (Maxalt); and Eletriptan (Relpax). 71% of reviewers reported a positive effect, while 13% reported a negative effect. The takeaway: Sumatriptan via injection is found to be one of the most effective (and more expensive) migraine treatments, and then Sumatriptan in oral form and Zolmitriptan in oral form. Generic and Brand Pills Online. Luckily, amino acid therapy provides a safe and effective alternative to Imitrex (sumatriptan). 46% of reviewers reported a positive effect, while 43% reported a negative effect Luckily, amino acid therapy provides a safe and effective alternative to Imitrex (sumatriptan). If I have a migraine, it takes an injection only 10 to 12 minutes. 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Imigran going over-the-counter (OTC) is huge for sufferers of migraines in the UK. In Sweden, sales have increased for both prescription and OTC triptans. 46% of reviewers reported a positive effect, while 43% reported a negative effect The new drug is to be called TREXIMET and according to the makers, was to be a vast improvement over Imitrex. Revenues for the drug in 2004 topped . This is also big news for GSK, the makers of Imigran/Imitrex. This study aimed to describe current prescribing and utilisation patterns of prescription and OTC triptans in Stockholm, Sweden The most commonly prescribed class of drugs for migraine are the triptans. Botox has an average rating of 5. Like Imitrex, it is made to be taken at the onset of a migraine, but is supposed to work faster and better to reduce migraine pain Alternatively, a person often feels like they have a ‘headache hangover’ after taking these medications. 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